Technical University of Munich
Associate Professorship of Biological Physics (Prof. Alim)
Ernst-Otto-Fischer-Str. 8
85748 Garching b. München
Our goal is to identify the physical principles governing life, thus providing new tools to overcome disease and invent smart and robotic materials. The architecture of vascular (flow) networks and their surprisingly complex functions are dynamically controlled by the interplay of flow and active, living matter. To uncover this inherently interdisciplinary process, we intertwine theory and experiment, thereby using a variety of approaches ranging from statistical physics and mechanics, cell, developmental, and synthetic biology to regenerative medicine.
Nature Physics
Abstract: A wire of motorized hinges learns, forgets, and relearns automatic responses on demand, uncovering the physical principles necessary to emulate autonomous learning of living matter.
Advanced Functional Materials
Abstract: Impaired vascular network remodeling is linked to tumor progression, impacting the efficacy of anti-vascular therapies. However, the interplay between blood flow and vascular endothelial growth factor…
Physical Review X
Abstract: From the vasculature of animals to the porous media making up batteries, the core task of flow networks is to transport solutes and perfuse all cells or media equally with resources. Yet, living flow…
Chem
Abstract: The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental principles of life and leveraging its unique…
Physical Review Fluids
Abstract: Through switching contraction patterns driving digestive flows, the small intestine balances nutrient uptake and waste removal. Complex segmentation contraction patterns are associated with higher…
Biophysical Journal
Abstract: Plant development relies on the precise coordination of cell growth, which is influenced by the mechanical constraints imposed by rigid cell walls. The hormone auxin plays a crucial role in regulating…
Proceedings of the National Academy of Sciences of the United States of America
Abstract: Multi-nucleated cells exist in all domains of life, ranging from animals, plants, and fungi to single-celled organisms such as the slime mold Physarum polycephalum. The large cell size, in the case of…
SciPost Physics Lecture Notes
Abstract: Flows are essential to transport resources over large distances. As soon as diffusion becomes time-limiting, flows are needed. Flows are key for the function of multiple human organs, from the blood…
PRX Life
Abstract: Network-forming organisms, like fungi and slime molds, dynamically reorganize their networks during foraging. The resulting rerouting of resource flows within the organism's network can significantly…
Current Biology
Abstract: Robust regulation of cell division is central to the formation of complex multi-cellular organisms and is a hallmark of stem cell activity. In plants, due to the absence of cell migration, the correct…
| Title | Dates | Duration | Type | Lecturer (assistant) |
|---|---|---|---|---|
| Advanced Statistical Physics |
|
4 | VO | |
| Current Developments in Physics of Biological Networks |
|
2 | PS | |
| Events "Talentmanagement and Diversity" |
|
0.1 | OV | |
| Exercise to Advanced Statistical Physics |
|
2 | UE |
K. Alim [L]
|
| Journal Club Biological Physics and Morphogenesis |
|
2 | SE | |
| Revision Course to Current Developments in Physics of Biological Networks |
|
2 | RE |
K. Alim [L]
|
| Seminar for Tutors in Advanced Statistical Physics |
|
2 | SE |
| Title | Dates | Duration | Type | Lecturer (assistant) |
|---|---|---|---|---|
| Biophysics |
|
4 | VO | |
| Current Developments in Physics of Biological Networks |
|
2 | PS | |
| Exercise to Biophysics |
|
2 | UE | |
| Journal Club Biological Physics and Morphogenesis |
|
2 | SE | |
| Mentoring in the Bachelor’s Program Physics |
|
0.2 | KO | |
| Revision Course to Current Developments in Physics of Biological Networks |
|
2 | RE |
K. Alim [L]
|