Prof. Dr. Michael Sattler
Technical University of Munich
Chair of Biomolecular NMR-Spectroscopy (Prof. Sattler)
Postal address
Lichtenbergstr. 4
85748 Garching b. München
- Phone: +49 (89) 289 - 52600
- Room: 5413.01.105
- Homepage
- michael.sattler@tum.de
Research
NMR and integrative structural biology and structure-based drug discovery
We study the structure, interactions and dynamics of biological macromolecules in solution using Nuclear Magnetic Resonance (NMR) spectroscopy and integrative structural biology.
Molecular mechanisms and regulation of proteins and RNAs in RNA-based gene regulation (alternative splicing and non-coding RNA pathways), and cellular signaling (molecular chaperones, peroxisome biogenesis), are unraveled by combining NMR with X-ray crystallography, small angle scattering (SAXS/SANS), cryo-EM and biophysical techniques.
Structure based drug discovery is used for the development of small molecule-based therapeutics.
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