Technical University of Munich
Chair of Neurobiological Engineering (Prof. Westmeyer)
Boltzmannstr. 11
85748 Garching b. München
We focus on biological engineering of genetically controlled molecular sensors and actuators for neuroimaging and -manipulation of organoids and preclinical model organisms to dissect cellular network function and aid future neurotherapies. Please find out more about our work here and here.
Microelectrode arrays (MEAs) can be used to record extracellular field potentials of cells, enabling investigations on neural or cardiac cellular electrical activity. However, conventionally used 2D…
Flexible, skin-conformable electrodes require materials that combine mechanical robustness, environmental stability, high electrical performance, and biocompatibility. Here, we present a flexible…
Magnetic nanoparticles have proven invaluable for biomechanical investigations due to their ability to exert localized forces. However, cellular delivery of exogenous magnetic agents often results in…
Magnetic nanoparticles have proven invaluable for biomechanical investigations due to their ability to exert localized forces. However, cellular delivery of exogenous magnetic agents often results in…
Advanced gene editing methods have accelerated biomedical discovery and hold great therapeutic promise, but safe and efficient delivery of gene editors remains challenging. In this study, we present a…
Bioluminescence is an attractive alternative to fluorescence for live-cell imaging; however, its low intensity has prevented widespread adoption. Specialized microscopes compensate by sacrificing…
This protocol provides comprehensive guidance for researchers, including those with limited electron microscopy (EM) experience, on the effective use of genetically encoded, multichannel EMcapsulin…
Understanding the functional connectivity and behavior of 3D cell cultures and organoids requires monitoring electrical activity across multiple planes. However, traditional planar microelectrode…
Emerging molecular therapies introduce enzymatic activity into cells by delivering genes, transcripts, or proteins. Owing to their robust cell-entry capacity, virus-like particles (VLPs) represent a…
