Sequence motif dynamics in RNA pools
In RNA world scenarios, pools of RNA oligomers form strongly interacting, dynamic systems, which enable molecular evolution. In such pools, RNA oligomers hybridize and dehybridize, ligate, and break,…
Prof. Dr. rer. nat. Ulrich Gerland
Technical University of Munich
Chair of Theoretical Physics - Theory of Complex Biosystems (Prof. Gerland)
Postal address
James-Franck-Str. 1
85748 Garching b. München
- Phone: +49 89 289 12394
- Room: 5101.01.333
- Homepage
- E-mail: gerland@tum.de
Publications
104 PublicationsSequence and chemical specificity define the functional landscape of intrinsically disordered regions
Intrinsically disordered regions (IDRs) pervasively engage in essential molecular functions, yet they are often poorly conserved as assessed by sequence alignment. To explore the seeming paradox of…
Erratum
(Cell Reports 40, 111290; August 30, 2022) When this article was originally published on August 30, 2022, an error during file preparation in the production process inadvertently affected some of the…
Mechanics and wrinkling patterns of pressurized bent tubes
Take a drinking straw and bend it from its ends. After sufficient bending, the tube buckles forming a kink, where the curvature is localized in a very small area. This instability, known generally as…
A roadmap toward the synthesis of life
The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental principles of life and leveraging its unique…
Force Generation by Enhanced Diffusion in Enzyme-Loaded Vesicles
The diffusion coefficient of some metabolic enzymes increases with the concentration of their cognate substrate, a phenomenon known as enhanced diffusion. In the presence of substrate gradients,…
Force Generation by Enhanced Diffusion in Enzyme-Loaded Vesicles
The diffusion coefficient of some metabolic enzymes increases with the concentration of their cognate substrate, a phenomenon known as enhanced diffusion. In the presence of substrate gradients,…
A quantitative model of enzyme-free copying of RNA with dimers
The transfer of genetic information from one RNA strand to a daughter strand in the absence of polymerases could have initiated prebiotic evolution. This reaction, driven by base pairing and chemical…
Template-based copying in chemically fuelled dynamic combinatorial libraries
One of science’s greatest challenges is determining how life can spontaneously emerge from a mixture of molecules. A complicating factor is that life and its molecules are inherently unstable—RNA and…
From Brownian to Deterministic Motor Movement in a DNA-Based Molecular Rotor
Molecular devices that have an anisotropic periodic potential landscape can be operated as Brownian motors. When the potential landscape is cyclically switched with an external force, such devices can…
Winter term 2025/26
Summer term 2026
| Title | Dates | Duration | Type | Lecturer (assistant) |
|---|---|---|---|---|
| Biomolecular Systems |
|
2 | SE | |
| Current Topics in Theory of Complex Bio-Systems |
|
2 | PS | |
| Exercise to Theory of Stochastic Processes |
|
2 | UE |
U. Gerland [L]
|
| Seminar for Tutors in Theory of Stochastic Processes |
|
2 | SE | |
| Theory of Stochastic Processes |
|
4 | VO |