Technical University of Munich
Assistant Professorship of Biosystems Chemistry of Natural Products (Prof. Benitez Mateos)
Lichtenbergstr. 4
85748 Garching b. München
Prof. Benítez-Mateos (*1991) conducts research on sustainable biocatalysis for the synthesis of natural products with relevance as pharmaceuticals, food additives, and agrochemicals. Her group aims to develop highly stable and efficient enzymatic cascades by integrating approaches from bioengineering, enzyme immobilization, and (flow) chemistry. A particular emphasis of her laboratory is on elucidating the molecular mechanisms of intrinsically disordered proteins (IDPs) and their applications in biotechnology and biocatalysis.
Nature Communications
Abstract: Biomolecular condensates can affect enzymatic reactions by locally changing not only concentrations of molecules but also their environment. Since protein conformations can differ between the dense…
Chimia
Abstract: Enzymes are emerging as a central element of green chemistry due to their high selectivity, biodegradability, and biocompatibility. However, their application in biotechnology is often limited by…
ChemCatChem
Abstract: In this perspective article, we celebrate the accomplishments of female-led research groups in biocatalysis. Through this initiative, we aim to showcase the breadth and excellence of women's research…
Nature Communications
Abstract: The mechanisms that underlie the regulation of enzymatic reactions by biomolecular condensates and how they scale with compartment size remain poorly understood. Here we use intrinsically disordered…
ChemCatChem
Abstract: l-Pipecolic Acid (l-PA) is a valuable building block for the synthesis of pharmaceuticals such as anesthetics and immunosuppressants. Thus, more efficient and greener strategies are desired for its…
ACS Sustainable Chemistry and Engineering
Abstract: Cell-free biocatalysis is gaining momentum in producing value-added chemicals, particularly in stepwise reaction cascades. However, the stability of enzyme cascades in industrial settings is often…
Journal of Flow Chemistry
Abstract: Flow biocatalysis has emerged as an empowering tool to boost the potential of enzymatic reactions towards more automatized, sustainable, and generally efficient synthetic processes. In the last…
Chimia
Abstract: Enzymes are natural catalysts which are gaining momentum in chemical synthesis due to their exquisite selectivity and their biodegradability. However, the cost-efficiency and the sustainability of the…
Applied Microbiology and Biotechnology
Abstract: Abstract: Extremophilic microorganisms, which are resistant to extreme levels of temperature, salinity, pH, etc., have become popular tools for biotechnological applications. Due to their availability…
Nature Chemistry
Abstract: Enzyme cascades are a powerful technology to develop environmentally friendly and cost-effective synthetic processes to manufacture drugs, as they couple different biotransformations in sequential…
| Title | Dates | Duration | Type | Lecturer (assistant) |
|---|---|---|---|---|
| Physical Biochemistry, Seminar (CH0410b) |
|
2 | SE |
| Title | Dates | Duration | Type | Lecturer (assistant) |
|---|---|---|---|---|
| Recent Advances in Sustainable Biocatalysis |
|
1 | SE | |
| Research Internship Biochemistry 1 (CH0554) |
|
16 | FO | |
| Research Internship Biochemistry 2 (CH0555) |
|
12 | FO | |
| Research Internship with Focus on Chemical Aspects (CH0510) |
|
8 | FO |