Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Abstract: In RNA world scenarios, pools of RNA oligomers form strongly interacting, dynamic systems, which enable molecular evolution. In such pools, RNA oligomers hybridize and dehybridize, ligate, and break,…
Nature Cell Biology
Abstract: Intrinsically disordered regions (IDRs) pervasively engage in essential molecular functions, yet they are often poorly conserved as assessed by sequence alignment. To explore the seeming paradox of…
Cell Reports
Abstract: (Cell Reports 40, 111290; August 30, 2022) When this article was originally published on August 30, 2022, an error during file preparation in the production process inadvertently affected some of the…
Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Abstract: Take a drinking straw and bend it from its ends. After sufficient bending, the tube buckles forming a kink, where the curvature is localized in a very small area. This instability, known generally as…
Chem
Abstract: The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental principles of life and leveraging its unique…
Nano Letters
Abstract: The diffusion coefficient of some metabolic enzymes increases with the concentration of their cognate substrate, a phenomenon known as enhanced diffusion. In the presence of substrate gradients,…
Nano Letters
Abstract: The diffusion coefficient of some metabolic enzymes increases with the concentration of their cognate substrate, a phenomenon known as enhanced diffusion. In the presence of substrate gradients,…
Nucleic Acids Research
Abstract: The transfer of genetic information from one RNA strand to a daughter strand in the absence of polymerases could have initiated prebiotic evolution. This reaction, driven by base pairing and chemical…
Nature Chemistry
Abstract: One of science’s greatest challenges is determining how life can spontaneously emerge from a mixture of molecules. A complicating factor is that life and its molecules are inherently unstable—RNA and…
Nano Letters
Abstract: Molecular devices that have an anisotropic periodic potential landscape can be operated as Brownian motors. When the potential landscape is cyclically switched with an external force, such devices can…