Technische Universität München
Professur für Experimental Biophysics (Prof. Duderstadt)
James-Franck-Str. 1
85748 Garching b. München
Science Advances
Abstract: During chromosome replication, unwinding by the helicase and synthesis by the polymerases can lead to overwinding and supercoiling of DNA. The mechanical consequences of these events and resulting…
Methods in molecular biology (Clifton, N.J.)
Abstract: Our understanding of biomolecular dynamics has been revolutionized with the advent of techniques that enable the manipulation of forces and torques at the single-molecule level. However, the…
Nature Structural and Molecular Biology
Abstract: Gene expression during natural and induced reprogramming is controlled by pioneer transcription factors that initiate transcription from closed chromatin. Nr5a2 is a key pioneer factor that regulates…
Life Science Alliance
Abstract: Fun30 is the prototype of the Fun30-SMARCAD1-ETL subfamily of nucleosome remodelers involved in DNA repair and gene silencing. These proteins appear to act as single-subunit nucleosome remodelers, but…
Nature
Abstract: Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)1–3, which contribute to transcription, recombination and genomic stability4,5. Cohesin extrudes DNA into loops…
Nucleic Acids Research
Abstract: Chromosome replication depends on efficient removal of nucleosomes by accessory factors to ensure rapid access to genomic information. Here, we show this process requires recruitment of the nucleosome…
eLife
Abstract: The rapid development of new imaging approaches is generating larger and more complex datasets, revealing the time evolution of individual cells and biomolecules. Single-molecule techniques, in…
Cell Reports
Abstract: Fundamental to our understanding of chromosome duplication is the idea that replication origins function both as sites where MCM helicases are loaded during the G1 phase and where synthesis begins in…
Small
Abstract: Cytoskeletal motors transform chemical energy into mechanical work to drive essential cellular functions. Optical trapping experiments have provided crucial insights into the operation of these…
Science
Abstract: Inflammasomes function as intracellular sensors of pathogen infection or cellular perturbation and thereby play a central role in numerous diseases. Given the high abundance of NLRP1 in epithelial…
| Titel | Termine | Dauer | Art | Vortragende/r (Mitwirkende/r) |
|---|---|---|---|---|
| Biophysik der Zelle 1 – Mechanik und Dynamik biologischer Makromoleküle |
|
2 | VO | |
| Makromolekulare Maschinen in der DNS-Replikation |
|
2 | PS | |
| Physikalische Biochemie, Vortragsseminar (CH0410b) |
|
2 | SE | |
| Recent Advances in Single-Molecule Imaging of Protein Nucleic Acid Complexes |
|
3 | SE | |
| Repetitorium zu Makromolekulare Maschinen in der DNS-Replikation |
|
2 | RE |
K. Duderstadt [L]
|
| Rezeption wissenschaftlicher Literatur (CH5041) |
|
5 | SE |
| Titel | Termine | Dauer | Art | Vortragende/r (Mitwirkende/r) |
|---|---|---|---|---|
| Biophysik der Zelle 2 |
|
2 | VO | |
| Makromolekulare Maschinen in der DNS-Replikation |
|
2 | PS | |
| Recent Advances in Single-Molecule Imaging of Protein Nucleic Acid Complexes |
|
3 | SE | |
| Repetitorium zu Biophysik der Zelle |
|
2 | RE |
K. Duderstadt [L]
|
| Repetitorium zu Makromolekulare Maschinen in der DNS-Replikation |
|
2 | RE |
K. Duderstadt [L]
|
| Seminar zu Biophysik der Zelle |
|
2 | PS |