Dr. rer. nat. Martin Kulke
Dr. rer. nat. Martin Kulke
Technical University of Munich
Chair of Theoretical Biophysics - Biomolecular Dynamics (Prof. Zacharias)
Postal address
Ernst-Otto-Fischer-Str. 8
85748 Garching b. München
- Phone: +49 (89) 289 - 13766
- Fax: +49 (89) 289 - 12444
- Room: 5415.EG.048 Homepage: https://www.groups.ph.tum.de/t38/home/
- martin.kulke@tum.de
Research Interests
- Protein-protein and protein-membrane interfaces
- Dynamic properties of protein, lipids and small organic compounds in liquid environments
- Enhanced sampling techniques
- Multiscale modeling
Publications
| Year | Authors, Title, Journal |
| 2024 | Parson, W.W., Huang, J., Kulke, M., Vermaas J.V., Kramer D.M. Electron transfer in a crystalline cytochrome with four hemes The Journal of Chemical Physics 2024, 160 (6), 065101 |
| 2024 | Kulke, M., Kurtz, E., Boren, D.M., Olson, D.M., Koenig, A.M., Hoffmann-Benning, S., Vermaas, J.V. PLAT domain protein 1 (PLAT1/PLAFP) binds to the Arabidopsis thaliana plasma membrane and inserts a lipid Plant Science 2024, 338, 111900 |
| 2023 | Weraduwage S.M., Whitten, D., Kulke, M., Sahu, A., Vermaas, J.V., Sharkey, T.D. The isoprene-responsive phosphoproteome provides new insights into putative signalling pathways and novel roles of isopren Plant, Cell, & Environment 2023, pce.14776 |
| 2023 | Kulke., M.; Olson, D.M., Huang, J., Kramer, D.M., Vermaas, J.V. Long-Range Electron Transport Rates Depend on Wire Dimensions in Cytochrome Nanowires Small 2023, 19, 2304013 |
2023
| Kulke, M., Weraduwage, S. M., Sharkey, T. D., Vermaas, J. V. Nanoscale Simulation of the Thylakoid Membrane Response to Extreme Temperatures. Plant Cell & Environment 2023, pce.14609 |
| 2023 | Weraduwage, S. M., Sahu, A., Kulke, M., Vermaas, J. V., Sharkey, T. D. Characterization of Promoter Elements of Isoprene‐responsive Genes and the Ability of Isoprene to Bind START Domain Transcription Factors Plant Direct 2023, 7 (2) |
| 2023 | Sarkar, D., Kulke, M., Vermaas, J. V. LongBondEliminator: A Molecular Simulation Tool to Remove Ring Penetrations in Biomolecular Simulation Systems Biomolecules 2023, 13 (1), 107 |
| 2022 | Kulke, M., Vermaas, J. V. Reversible Unwrapping Algorithm for Constant-Pressure Molecular Dynamics Simulations J. Chem. Theory Comput. 2022, 18 (10), 6161–6171 |
| 2022 | Schulig, L., Geist, N., Delcea, M., Link, A., Kulke, M. Fundamental Redesign of the TIGER2hs Kernel to Address Severe Parameter Sensitivity J. Chem. Inf. Model. 2022, 62 (17), 4200–4209 |
| 2022 | Ayala Mariscal, S. M., Pigazzini, M. L., Richter, Y., Özel, M., Grothaus, I. L.,Protze, J., Ziege, K., Kulke, M., ElBediwi, M., Vermaas, J. V., Colombi Ciacchi, L., Köppen, S., Liu, F., Kirstein, J. Identification of a HTT-Specific Binding Motif in DNAJB1 Essential for Suppression and Disaggregation of HTT Nat Commun 2022, 13 (1), 4692 |
| 2021 | Zwicker, P., Geist, N., Göbler, E., Kulke, M., Schmidt, T., Hornschuh, M., Lembke, U., Prinz, C., Delcea, M., Kramer, A., Müller, G. Improved Adsorption of the Antimicrobial Agent Poly (Hexamethylene) Biguanide on Ti-Al-V Alloys by NaOH Treatment and Impact of Mass Coverage and Contamination on Cytocompatibility Coatings 2021, 11 (9), 1118 |
| 2021 | Kulke, M., Nagel, F., Schulig, L., Geist, N., Gabor, M., Mayerle, J., Lerch, M. M., Link, A., Delcea, M. A A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies J. Inflamm. Res. 2021, Volume 14, 2111–2119 |
| 2021 | Schulig, L., Grabarczyk, P., Geist, N., Delin, M., Forkel, H., Kulke, M., Delcea, M., Schmidt, C. A., Link, A. Unveiling the N-Terminal Homodimerization of BCL11B by Hybrid Solvent Replica-Exchange Simulations Int. J. Mol. Sci. 2021, 22 (7), 3650 |
| 2021 | Buchholz, I., McDonnell, T., Nestler, P., Tharad, S., Kulke, M., Radziszewska, A., Ripoll, V. M., Schmidt, F., Hammer, E., Toca-Herrera, J. L., Rahman, A., Delcea, M. Specific Domain V Reduction of Beta-2-Glycoprotein I Induces Protein Flexibility and Alters Pathogenic Antibody Binding Sci. Rep. 2021, 11 (1), 4542 |
| 2020 | Kulke, M., Langel, W. Molecular Dynamics Simulations to the Bidirectional Adhesion Signaling Pathway of Integrin ΑVβ3 Proteins Struct. Funct. Bioinforma. 2020, 88 (5), 679–688 |
| 2019 | Kulke, M., Uhrhan, M., Geist, N., Brüggemann, D., Ohler, B., Langel, W., Köppen, S. Phosphorylation of Fibronectin Influences the Structural Stability of the Predicted Interchain Domain J. Chem. Inf. Model. 2019, 59 (10), 4383–4392 |
| 2019 | Geist, N., Kulke, M., Schulig, L., Link, A., Langel, W. Replica-Based Protein Structure Sampling Methods II: Advanced Hybrid Solvent TIGER2hs J. Phys. Chem. B 2019, 123 (28), 5995–6006 |
| 2019 | Janke, U., Kulke, M., Buchholz, I., Geist, N., Langel, W., Delcea, M. Drug-Induced Activation of Integrin Alpha IIb Beta 3 Leads to Minor Localized Structural Changes PLoS One 2019, 14 (4), e0214969 |
| 2019 | Kulke, M. A Molecular Model for an Adhesion Complex in the Extracellular Matrix of Bone Cells PhD Thesis, University of Greifswald, 2019 |
| 2018 | Kulke, M., Geist, N., Möller, D., Langel, W. Replica-Based Protein Structure Sampling Methods: Compromising between Explicit and Implicit Solvents J. Phys. Chem. B 2018, 122 (29), 7295–7307 |
| 2017 | Kulke, M., Geist, N., Friedrichs, W., Langel, W. Molecular Dynamics Simulations on Networks of Heparin and Collagen Proteins Struct. Funct. Bioinforma. 2017, 85 (6), 1119–1130 |
| 2014 | Aliev, A. E., Kulke, M., Khaneja, H. S., Chudasama, V., Sheppard, T. D., Lanigan, R. M. Motional Timescale Predictions by Molecular Dynamics Simulations: Case Study Using Proline and Hydroxyproline Sidechain Dynamics Proteins Struct. Funct. Bioinforma. 2014, 82 (2), 195–215 |