Riboswitch inspired toehold regulators

Combining the switching principle of riboswitches with that of toehold switches, Tianhe (Mark) Wang created a series of novel translational and transcriptional gene regulators, including the first synthetic switch utilizing Rho-dependent termination.

Read the full story in Nucleic Acids Research:

Tianhe Wang & Friedrich C. Simmel, Riboswitch-inspired toehold riboregulators for gene regulation in Escherichia coli, Nucleic Acids Research 50, 4784-4798 (2022).