2018

• From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands
• In vivo characterization of four 68Ga-labeled multimeric RGD peptides to image αvβ3 integrin expression in two human tumor xenograft mouse models
• N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent
• Therapeutic Radiopharmaceuticals Targeting Integrin αvβ6

2017

• A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

2016

• In-vivo PET imaging of the "cancer integrin" αvβ6 using gallium-68 labelled cyclic RGD nonapeptides
• Variation of Specific Activities of ⁶⁸Ga-Aquibeprin and ⁶⁸Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins a₅b₁ and a_vb₃
• Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer

2015

• In vivo biokinetic and metabolic characterization of the 68Ga-labelled α5β1-selective peptidomimetic FR366

Ältere

• Comparison of cyclic RGD peptides for αvβ3 integrin detection in a rat model of myocardial infarction
• Be spoilt for choice with radiolabelled RGD peptides: Preclinical evaluation of 68 Ga-TRAP(RGD)3
• 68Ga-NODAGA-RGD is a suitable substitute for 18F-Galacto-RGD and can be produced with high specific activity in a cGMP/GRP compliant automated process