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Transcriptional interference influences gene regulatory toehold switches


A study of this effect by Elisabeth Falgenhauer, Andrea Mückl and Matthaeus Schwarz-Schilling has just been published:

Falgenhauer, E., Mückl, A., Schwarz-Schilling, M. & Simmel, F. C. Transcriptional Interference in Toehold Switch-Based RNA Circuits. ACS Synth Biol (2022) doi:10.1021/acssynbio.1c00486.

https://pubs.acs.org/doi/10.1021/acssynbio.1c00486