Prof. Michael Sattler


Foto von Michael Sattler

Prof. Dr. Michael Sattler

Technische Universität München

Lehrstuhl für Biomolekulare NMR-Spektroskopie (Prof. Sattler)

Postadresse

Postal:
Lichtenbergstr. 4
85748 Garching b. München

Research

NMR and integrative structural biology and structure-based drugdiscovery

We study the structure, molecular recognition and dynamics of biological macromolecules in solution using Nuclear Magnetic Resonance (NMR) spectroscopy.

NMR is combined in an integrative structural biology approach with X-ray crystallography, Small Angle X-ray and/or Neutron Scattering (SAXS/SANS), cryo-EM and biophysical techniques to understand molecular mechanisms of regulatory protein complexes in RNA-based gene regulation (e.g. alternative splicing and non-coding RNAs pathways), and cellular signaling (molecular chaperones, peroxisome biogenesis) in physiological and disease-linked pathways. 

NMR and integrative structural biology are used to develop novel therapeutic approaches employing structure-based drug discovery of small molecule and RNA-based therapeutics.

Winter term 2023/24

TitleDatesDurationTypeLecturer (assistant)
Biological Chemistry (CH3181a, CH0448a)Link2VO
Biological Chemistry, Exercise (CH0448b)Link2UE
Biomolecular NMR-Spectroscopy (CH3184a)Link2VO
Lecture Series: Bayerisches NMR Zentrum (BNMRZ)Link2KO
Organic Chemistry Practical Course (NAT0012)Link5PR
Physical Biochemistry, Seminar (CH0410b)Link2SE
Practical Aspects of NMRLink1SE
Research Laboratory Course for Biochemists (CH0943)Link6PR
Research Laboratory Course in Biological Chemistry 1 (CH0554)Link10PR
Research Laboratory Course in Biological Chemistry 2 (CH0555)Link8PR
Research Laboratory Course with Focus in Chemistry (CH0510)Link6PR
Research SeminarLink4SE